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Index > Protein center > Aldh3a1(Gene name) > Rat
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  • Aldh3a1 (Gene name),
  • Aldehyde dehydrogenase, dimeric NADP-preferring (Protein name ),  AL3A1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Aldh3a1(Aldd;Aldh3);
    Protein name:
    Aldehyde dehydrogenase, dimeric NADP-preferring;
    Alternative:
    HTC-ALDH;Aldehyde dehydrogenase family 3 member A1;Tumor-associated aldehyde dehydrogenase;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    453
    Sequence:
    50:
    MSSISDTVKR | AREAFNSGKT | RSLQFRIQQL | EALQRMINEN | LKSISGALAS | 
    100:
    DLGKNEWTSY | YEEVAHVLEE | LDTTIKELPD | WAEDEPVAKT | RQTQQDDLYI | 
    150:
    HSEPLGVVLV | IGAWNYPFNL | TIQPMVGAVA | AGNAVILKPS | EVSGHMADLL | 
    200:
    ATLIPQYMDQ | NLYLVVKGGV | PETTELLKER | FDHIMYTGST | AVGKIVMAAA | 
    250:
    AKHLTPVTLE | LGGKSPCYVD | KDCDLDVACR | RIAWGKFMNS | GQTCVAPDYI | 
    300:
    LCDPSIQNQI | VEKLKKSLKD | FYGEDAKQSR | DYGRIINDRH | FQRVKGLIDN | 
    350:
    QKVAHGGTWD | QSSRYIAPTI | LVDVDPQSPV | MQEEIFGPVM | PIVCVRSLEE | 
    400:
    AIQFINQREK | PLALYVFSNN | EKVIKKMIAE | TSSGGVTAND | VIVHITVPTL | 
    450:
    PFGGVGNSGM | GAYHGKKSFE | TFSHRRSCLV | KSLLNEEAHK | ARYPPSPAKM | 
    453:
    PRH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    E11318h
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    96T
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    ELISA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
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    E11318r
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    Packing:
    96T
    ELISA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
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    E11318d
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    Packing:
    96T
    ELISA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
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    E11318m
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    Packing:
    96T
    ELISA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    E11318b
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    Packing:
    96T
    CLIA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    U11318d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    U11318m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    U11318r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    U11318h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    U11318b
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    P11318Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    P11318Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Polyclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Polyclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Cat.:
    P11318Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Monoclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Monoclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Monoclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Monoclonal Antibody for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Protein for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Protein for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Protein for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Protein for Rat Aldehyde dehydrogenase, dimeric NADP-preferring
    Protein for Rat Aldehyde dehydrogenase, dimeric NADP-preferring

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and complete nucleotide sequence of a full-length cDNA encoding a catalytically functional tumor-associated aldehyde dehydrogenase."
      Jones D.E. , Brennan M.D. , Hempel J. , Lindahl R.
      Proc. Natl. Acad. Sci. U.S.A.85:1782-1786(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    3. 3.
      "Inducible (class 3) aldehyde dehydrogenase from rat hepatocellular carcinoma and 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated liver: distant relationship to the class 1 and 2 enzymes from mammalian liver cytosol/mitochondria."
      Hempel J. , Harper K. , Lindahl R.
      Biochemistry28:1160-1167(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
    4. 4.
      "Organization and characterization of the rat class 3 aldehyde dehydrogenase gene."
      Asman D.C. , Takimoto K. , Pitot H.C. , Dunn T.J. , Lindahl R.
      J. Biol. Chem.268:12530-12536(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GENE STRUCTURE
    5. 5.
      "Preliminary crystallographic analysis of class 3 rat liver aldehyde dehydrogenase."
      Rose J.P. , Hempel J. , Kuo I. , Lindahl R. , Wang B.-C.
      Proteins8:305-308(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS)
    6. 6.
      "The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold."
      Liu Z.-J. , Sun Y.J. , Rose J.P. , Chung Y.-J. , Hsiao C.D. , Chang W.-R. , Kuo I. , Perozich J. , Lindahl R. , Hempel J. , Wang B.-C.
      Nat. Struct. Biol.4:317-326(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS)
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